Every amino acid also has another atom or group of atoms bonded to the central atom known as the R group ( Figure 3.22).įigure 3.23 There are 20 common amino acids commonly found in proteins, each with a different R group (variant group) that determines its chemical nature. Each amino acid has the same fundamental structure, which consists of a central carbon atom, or the alpha ( α) carbon, bonded to an amino group (NH 2), a carboxyl group (COOH), and to a hydrogen atom. ![]() ![]() Amino AcidsĪmino acids are the monomers that comprise proteins. Two rare new amino acids were discovered recently (selenocystein and pirrolysine), and additional new discoveries may be added to the list. Different arrangements of the same 20 types of amino acids comprise all proteins. Changes in temperature, pH, and exposure to chemicals may lead to permanent changes in the protein's shape, leading to loss of function, or denaturation. Protein shape is critical to its function, and many different types of chemical bonds maintain this shape. For example, hemoglobin is a globular protein, but collagen, located in our skin, is a fibrous protein. Some proteins are globular in shape whereas, others are fibrous in nature. Proteins have different shapes and molecular weights. Table 3.1 lists the primary types and functions of proteins. For example, insulin is a protein hormone that helps regulate the blood glucose level. Hormones are chemical-signaling molecules, usually small proteins or steroids, secreted by endocrine cells that act to control or regulate specific physiological processes, including growth, development, metabolism, and reproduction. An example of an enzyme is salivary amylase, which hydrolyzes its substrate amylose, a component of starch. Note that all enzymes increase the reaction rate and, therefore, are organic catalysts. Those that build more complex molecules from their substrates are anabolic enzymes, and enzymes that affect the rate of reaction are catalytic enzymes. We call enzymes that break down their substrates catabolic enzymes. The enzyme may help in breakdown, rearrangement, or synthesis reactions. Each enzyme is specific for the substrate (a reactant that binds to an enzyme) upon which it acts. Types and Functions of ProteinsĮnzymes, which living cells produce, are catalysts in biochemical reactions (like digestion) and are usually complex or conjugated proteins. They are all, however, amino acid polymers arranged in a linear sequence. Their structures, like their functions, vary greatly. Each cell in a living system may contain thousands of proteins, each with a unique function. They may serve in transport, storage, or membranes or they may be toxins or enzymes. Proteins may be structural, regulatory, contractile, or protective. Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. ![]()
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If that warning is too late for you look through the information below to see if your issue is being experienced by others and what the best way to tackle the problem is. If is usually the case that when Apple launches a new version of macOS we see various complaints from people suffering from issues following the update.įor this reason it may be worth waiting until Apple issues the first update to Monterey – probably macOS 12.1, at which point the biggest issues will hopefully have been ironed out. What are the known problems with Monterey? We run through all the Macs that are compatible with Monterey here: Which Monterey features run on my Mac to find out which Monterey features your Mac supports. There are some features that require an M1-powered Mac, for example. However, just because your Mac can run Monterey doesn’t mean that you will get all the features. Mac mini models from autumn 2014 or later.Here’s an overview of the Macs that can run Monterey: ![]() The biggest changes in the beta version so far have included changes to the layout of the address bar and tabs in Safari. The betas usually refine and fix features, and sometimes introduce problems that are fixed in subsequent updates – which is why Apple doesn’t recommend installing a beta on the Mac you use as your main machine. Be warned though, beta software may be buggy and cause problems with your Mac. ![]() If you want access to the beta versions of macOS read how to install the macOS beta. The beta program allows developers and public beta testers to try out the new software before it is released to the public. It’s very unlikely that Apple would update Monterey for any other reason though now that Ventura is on the horizon.Īpple has been running a Apple Beta Software Program for Monterey since it was first announced back in June 2021. We don’t expect that there will be another beta version of Monterey, although it is possible that Apple will be alerted to further security issues. What’s the latest beta version of macOS Monterey? Version 12.2 followed the release of macOS 12.1 on December 13, 2021, which introduced SharePlay, Apple Music Voice Plan, Digital Legacy, changes to Memories in Photos, and some bug fixes. Prior to that macOS Monterey 12.2 came out on January 26, 2022. That update followed the major release of macOS 12.3 on March 14, which brought with it the long-awaited Universal Control feature that lets you share a mouse and keyboard between Macs and iPads. Apple released macOS 12.3.1 on March 31, 2022. It includes updates to the Podcasts app, the Studio Display Fireware Update 15.5, and bug fixes. Prior to macOS 12.5, macOS 12.4 was released on May 16, 2022. There are also a number of security updates. And a problem with Safari tabs is also addressed. According to Apple it incudes “enhancements, bug fixes and security updates.” There’s also the new option to restart a live sports game already in-progress and pause, rewind, or fast-forward. Prior to that the latest version was macOS 12.5, which was released on July 20. The latest version, macOS Monterey 12.5.1, was released on August 17 and contains important security updates that address a serious vulnerability in the Kernel and WebKit, both of which were identified by an anonymous researcher. However, since the release of Monterey Apple has continued to update it, adding new features and fixing (and sometimes adding) bugs and vulnerabilities. You may also like to read our Monterey vs Big Sur comparison. Read all about Monterey and its features in our Monterey Superguide. What’s the latest version of macOS Monterey?Īpple made macOS Monterey (macOS 12) available to download (as long as you have a compatible Mac) on Monday, October 25, 2021, at around 10 am PT (6 pm UK time). ![]() It is a popular part of the treatment regimen for people living with cancer and AIDS.Īn analysis by the Wall Street Journal stated the sale only made sense if the company found a way to "substantially" increase the price of the drug. This company recently acquired a firm that has been making a drug that treats parasites in people with weak immune systems for 62 years. One is a pharmaceutical company whose stated corporate values appear to be at odds with recent actions. ![]() Should they need more, the business world constantly produces case studies of all of the bad things that can happen when people get greedy. ![]() The concussion-related lawsuits and the negative publicity they generated should be all the proof they need. Merchandising, television contracts, concessions tickets and more generate huge profits for most involved.īut the league, like any business, should be wary of pursuing the dollar and nothing else. Josh Shaw Academy Sports + Outdoors Hugh R.The National Football League is a hugely successful business. #HeatHealth #HealthEquity #sdoh #UNGA #onamission United Nations Carmen Bauza UPS The Home Depot CVS Health Walmart Lowe's Companies, Inc. It's time everyone understands the impact of Heat on our Health and to create dynamic partnerships that provide better access to solutions that not only improve comfort and safety in the heat, but simultaneously produce better health outcomes along the way. Heat exacerbates nearly every pre-existing medical condition, reduces cognition and reaction times, and crushes performance. Heat has an extreme disproportionate impact on low-income, Hispanic, and Black demographics who are up to 91% more likely to die of a heat-related illnesses. Did you know that Heat is the #1 weather-related killer on earth? Heat costs the global economy over $1 Trillion/year in losses and is the #1 cause of exertion-related deaths amongst laborers (#3 overall). There, with global industry leaders in Healthcare, Pharma and Retail, I got to share the MISSION story of our nearly 15 years of science, research, innovations and collaborations, providing the blueprint for addressing the #1 environmental social determinant of health on earth: Extreme Heat. Honored, humbled, and inspired to have been selected as a delegate to the Health Equity Forum at the United Nations General Assembly yesterday in New York City. In his #TEDxTalk titled: Athletes as Leaders: Why they represent the missing link in today's leadership crisis, this session will make you rethink a new leadership pipeline that connects our need for leaders with a pool of talent that instinctively has the skills we lack, yet few know about. He is the Co-Founder and President of MISSION, the global leader in Cooling and Heat-Relief Gear for active consumers, and author of “Team WORKS!,” a book that converges athletic principles with business success. With a passion for using athletic-performance principles to achieve business success, Chris has developed an established track record of launching and scaling several multi-million dollar ventures. We are super thrilled to introduce our next speaker, Chris Valletta, an award-winning entrepreneur, author, media contributor and former NFL Player. 77% of CEO’s agree: The #1 threat we face as a country are a lack of Leadership skills – aka “Soft Skills.” While the talent experts and education system continue to groom young people full of credentials, we are missing, perhaps ignoring, a talent pool of a different kind – one that is highly versed in the critical leadership skills missing most: Athletes. Pollen contains high-quality proteins and amino acids that may aid such absorption ( 33). This uptick is likely due to the fact that pollen contains vitamin C and bioflavonoids, which boost iron absorption ( 33).Īdditionally, healthy rats fed pollen absorbed more calcium and phosphorus from their diet. Some evidence suggests bee pollen may improve your body’s utilization of nutrients.įor instance, iron-deficient rats absorbed 66% more iron when pollen was added to their diet. May improve nutrient utilization, metabolism and longevity It may also improve cholesterol levels.ġ0. Studies have shown that bee pollen may alleviate several menopausal discomforts, including hot flashes. In addition, these supplements helped lower “bad” LDL cholesterol and raise “good” HDL cholesterol ( 32). Moreover, a three-month study showed that women taking bee pollen supplements experienced significantly fewer menopausal symptoms. These women indicated other health improvements as well, such as better sleep, reduced irritability, less joint pain and improved mood and energy ( 31). In another study, 65% of women taking a pollen supplement experienced fewer hot flashes. In one study of women with breast cancer, 71% of the participants felt that their menopausal symptoms improved while taking bee pollen ( 30). Studies show that bee pollen may alleviate several menopausal symptoms. Menopause, which marks the cessation of menstruation in women, is often accompanied by uncomfortable symptoms such as hot flushes, night sweats, mood changes and sleep disturbances ( 30). May ease menopausal symptoms like hot flashes ![]() Summaryīee pollen contains a wide variety of antioxidants, which may protect your cells from damage caused by free radicals that are linked to chronic diseases, including cancer and type 2 diabetes.ĩ. Unless a plant source is specifically stated on the label, it can be difficult to determine where your bee pollen came from. However, bee pollen’s antioxidant content also depends on its plant source ( 7, 10). ![]() Test-tube, animal and some human studies have shown that bee pollen antioxidants can reduce chronic inflammation, eliminate harmful bacteria, fight infections and combat the growth and spread of tumors ( 9). Damage by free radicals is linked to chronic diseases such as cancer and type 2 diabetes ( 8). High antioxidant content protects from free radicals and chronic diseasesīee pollen is loaded with a wide variety of antioxidants, among them flavonoids, carotenoids, quercetin, kaempferol and agglutination ( 6, 7).Īntioxidants protect your body against potentially harmful molecules called free radicals. The exact nutrient composition depends on the plant source and season collected.Ģ. Summary Bee pollen contains over 250 biological substances, including protein, carbs, fats, vitamins, minerals, enzymes and antioxidants. ![]() In addition, bee pollen harvested during springtime has a significantly different amino acid composition than pollen collected during the summer ( 1). However, the pollen’s nutritional content depends on the plant source and season collected.įor instance, older studies have shown that bee pollen collected from pine plants has approximately 7% protein, while pollen collected from date palm packs closer to 35% protein ( 5). The latter category includes vitamins, minerals, antibiotics and antioxidants. It contains over 250 biologically active substances, including proteins, carbs, lipids, fatty acids, vitamins, minerals, enzymes and antioxidants ( 2).īee pollen granules consist of approximately ( 4): Share on Pinterest Westend61/Getty Imagesīee pollen boasts an impressive nutritional profile. ![]() Major improvements to the audio engine and overall performance.Enhanced music library features including support for editing song metadata, ratings, and comments in My Collection and My Files (macOS only).All-new stunning waveforms with crisp colors and updated overlays for beats, cue points, loops, downbeat anchors, and beats in negative time.UI refresh with new dashboard & settings.Starter Mode: our most powerful yet intuitive interface yet (iOS only).Fluid Beatgrid™: all-new, groundbreaking beat detection engine with support for tempo changes, automatic flexible grids, and so much more.Crossfader Fusion™: elevate your mix and apply creative effects as you transition between tracks.All-new Neural Mix™ 2.0: a new standard in performance and sound quality (jointly developed with AudioShake).Here are some of the highlights in version 5.0: Get ready to experience djay like never before! We're thrilled to introduce djay 5.0, our most significant update yet – free to existing djay users! This major update comes packed with new features, significant improvements, and groundbreaking innovations designed to enhance your DJing experience. DRM-protected songs are not supported and djay Pro can not access tracks from the Apple Music streaming service. To use songs from iCloud in djay Pro please download them first via the Music app. Streaming service availability and pricing may vary depending on country, currency and service. No recording available for streamed songs. The optional PRO subscription allows you to subscribe once and use djay Pro across all your Mac and iOS devices, including access to all PRO features, as well as 1000+ loops, samples, and visuals.Ī supported streaming subscription and an internet connection is required to access songs from a streaming service in djay Pro. Support for external audio input and microphones. ![]()
![]() If you’re seeking some spring sun, check out the theme parks in Orlando or live it up on Miami Beach, one of the liveliest and most beautiful beach destinations on the east coast. From impressive architecture to a thriving food scene and creative neighbourhoods, visit the vibrant city for its special and unique culture. Chicago, also known as the Windy City, will blow you away. From diverse international restaurants and high-end shops to street art and spacious parks, New York offers a little bit of everything. Tick the Big Apple off your travel bucket list in 2023 and set out to explore the stylish streets of New York. Aer Lingus is offering €100 off return flights to North America and with 15 direct routes from Ireland to choose from including Boston, New York, Newark, Chicago, Orlando, Miami, Washington DC, Philadelphia, Hartford, Seattle, San Francisco, Los Angeles and Toronto, there’s never been a better time to take 2023 to new heights (and sights). Get the new year off to a flying start with a trip to the U.S.A. Fare savings are valid for travel between 1st December 2022 – 28th March 2023. Sun-seekers can top up their vitamin D on the beaches of Lanzarote, Fuerteventura or Malaga, while ski enthusiasts can take to slopes from Lyon, Verona, Geneva, and Munich. ![]() To make the most of Aer Lingus’ amazing Black Friday deals, customers must book before midnight on Tuesday, 29 November, for travel between 1 January – 28 March 2023.įor those who prefer to travel a little closer to home, Aer Lingus is also offering up to 25% off return flights to many popular European destinations. Customers can bag €100 off return economy class flights to North America or €200 off return business class travel. Up to 25% off flights to Europe including winter sun destinations such as the Canary Islands, Lisbon, Malaga and moreĭublin, 22 November 2022 - Planning a spring-time trip to the States or seeking an extra special gift for the adventurer in your life this Christmas? Aer Lingus is here to help customers make great savings with the announcement of its Black Friday sale.€200 off return Business class flights to North America.€100 off return flights to North America.Press releaseBag a bargain with the Aer Lingus Black Friday Sale! November 22, 2022 ![]() If attaching a video or photo, terms of use apply. ![]() Have a breaking news tip or an idea for a story we should cover? Send it to Eyewitness News using the form below. * Download the abc7NY app for breaking news alerts Submit a tip or story idea to Eyewitness News New Yorkers struggling with a gambling addiction, or who know someone who is, can find help by calling the State's toll-free, confidential HOPEline at 1-877-8-HOPENY (1-87) or by texting HOPENY (467369). 20, 2021 (one ticket, from Maryland)įor more information about the New York lottery and to see lottery results, please visit nylottery.ny.gov ![]() Use the number buttons below to highlight the corresponding numbers in the results. Drawing: Ask for either Monday, Wednesday or Saturdays 9:22 p.m. If the calendar is only one month wide, make your. Look for your game using date and state filters. You are viewing the Illinois Lottery Plottery results calendar, ideal for printing or viewing winning numbers for the entire year. 6, 2023 (one ticket, from Washington state)ġ0. Find the latest daily and pick game winning numbers at a glance in the table below. 23, 2017 (one ticket, from Massachusetts)ĩ. If you have questions about the claims process, please see our FAQs, call the Player Hotline at 1-80, or email the Illinois Lottery Claims Department at. If you plan to claim your prize via a Claim Center, you MUST make an appointment. $768.4 million, Powerball, Ma(one ticket, from Wisconsin)Ĩ. Winnings over 10,000 must be claimed at a Claim Center or by mail. Latest New Jersey (NJ) Lottery Results and winning numbers for Pick 3, Pick 4, Cash 5, Mega Millions, Powerball & Best NJ Lottery Scratch Off Rankings If. $1.337 billion, Mega Millions, J(one ticket, from Illinois)Ħ. Here are the winning numbers in case you need to check your. 23, 2018 (one ticket, from South Carolina)Ĥ. Its the second time this year an Illinois player has won 1 million or more playing Mega Millions, according to Illinois Lottery. IOS and Android free SpanishDict Translator The only real downside of SayHi is a lack of offline access, but otherwise, it’s a fantastic free tool, especially for Android users who don’t have access to Speak and Translate. For language learners, there’s the companion “SayHi Learn” app, which includes educational tools for studying Spanish, French, Danish, and German. Spanish options are particularly robust, with eighteen areas covered in total.Īgain, you can choose if the voice is male or female, and select the speed of the voice. Words can be translated into the particular dialect of Arabic spoken in Egypt or Bahrain, for example, or the Mandarin spoken in mainland China or Taiwan. The app has strong support for regional language variations. Like many other conversation apps, it focuses on providing a user-friendly experience for conversations between people who don’t speak the same language. If you want an alternative to Speak & Translate (above), check out SayHi. IOS, free, or $5.99 per month / $59.99 per year SayHi Speak & Translate isn’t necessarily a tool for every traveler, but for those who want a better, more seamless conversational experience, it may well be worth the money. ![]() Pull out the credit card, however, and you’ll be rewarded with offline translation between ten languages, no limit on the number of daily translations, and removal of the ads. The ad-supported free version includes all of the basic features, and will be enough for many people. You can access your translation history (a handy tool for travelers!), and set various options such as how quickly the translated text is read out, or whether you’d prefer a male or female voice. Translations are generated from a range of sources, including Google Translate, Microsoft Translate, and others. The app covers 117 languages for text translation, 54 languages for voice translations, and even integrates with Apple Watch. It’s sleek and very easy to use, in contrast to the clunky Conversation portion of Google Translate. ![]() Looking for an app that specifically focuses on translating conversations? Speak & Translate will be right up your alley, even if the premium version comes with a relatively high price tag. While it’s great to be able to translate words and phrases when you need to, it’s even better to be able to learn at least the basics so you don’t always need to reach for your phone. The phrasebook feature alone makes Microsoft Translator a handy tool, especially if you pair it with Google Translate as well. That’s just the beginning, though, with many other options across several categories including dining, technology, health, emergency, and travel. Some are very general, such as “Thank you,” “How much?” or “Is there an ATM?” - the kind of basic, essential phrases we’re all likely to need on the road. Just like in the olden days of travel, when people carried around quaint phrasebooks with tattered pages, there’s a large list of useful phrases within the app. The translation aspect itself is probably inferior to Google Translate, but its the Phrasebook tool that makes Microsoft Translator stand out. Microsoft Translator is arguably the biggest alternative to Google’s version, with many of the same features. The app provides general translation functionality (via text, audio, or image), and you can pin translations for later reference. IOS and Android, free Microsoft Translator Google Translate is definitely the king, but there’s space for other translation apps as well. That “Conversation” feature is a bit clunky to use in the real world, for instance, and there are no phrasebooks, educational resources, or other tools to help learn the language yourself. The reality is that while it’s a great tool, it’s not perfect for every situation. “Conversation” mode seems tailor-made for travelers, translating speech in both directions as two people speak to each other in different languages.Ĭonveniently integrating with other apps for on-the-fly translation, and entirely free to use, you may wonder why we even need other translation apps if Google Translate is so good. ![]() It’s probably the best offline translator right now, with support for many (although not all) languages, and the volunteer community continually improves the translated results. ![]() With over 100 languages on the mobile app, half of which include translation of text from a photo, it’s the most comprehensive option available. Google Translate is an indispensable tool for any traveler. ![]() ![]() There are no complicated processes or confusing tools – just a few simple steps, and your footage is ready to go. With just a few clicks of a button, your video footage will start rendering to create beautiful high-resolution quality footage. Unlike Gigapixel AI for photos, Video Enhance AI can extrapolate more detail for an even more realistic look, given the amount of information available in a single video clip. Video Enhance AI was trained using a neural network that analyzes thousands of video pairs to learn how details usually get lost. Have you ever wanted your footage to look sharper with more detail? Take HD footage all the way up to 8K for use in high-quality projects. ![]() Trained on thousands of videos and combining information from multiple input video frames, Topaz Video Enhance AI enlarges your video up to 8K resolution with true details and motion consistency. Video Enhance AI is the perfect way to take good footage and make it great. Topaz Video Enhance AI beautiful video enlargements using machine learning. From old home movies to low-quality SD to DVD quality and more, Video Enhance AI will transform your videos into clean upscaled footage up to 8K resolution. v3.1.11 Released March 28th, 2023 Downloads: Windows Mac Changes from v3.1. Tuned Autopilot’s selection of Enhance models. Added sliders to Enhance models for more control. Full support for RAW images will be added later this month. Despite its reputation, 99 seems like a fair price to pay if youre serious about. Changes since 1.2.0: Added Apple Photos extension with full support for non-RAW images. The app promises to upscale images by up to 600, and the tool has made quite a name for itself among professional circles. Until now, there was no way to recreate a high-resolution video from low-resolution footage perfectly. Hello Everyone A new release of Topaz Video AI is now available. Topaz GigaPixel AI (99) If money is no object and you want the best upscaling tool money can buy, Gigapixel AI is the app for you. Topaz Video Enhance AI enlarges your video up to 8K resolution with true details and motion consistency. ![]() This will then be confirmed when you have completed checkout. You will be given the option to choose a collection day that suits you on the product page after entering your post code. We are doing all we can to ensure your collection is available on time. Once you have chosen a slot, this date and time is unable to be amended.įor the safety of our customers and colleagues, extra measures have been put in place that may result in your click & collect order taking longer than normal to be ready. If you have ordered a built bike you will have been asked to book a collection day and time to safely collect your bike. Please provide a mobile phone number and email address during the checkout process so we can notify you when you product is ready to collect. In this instance, please make yourself known to the Halfords colleague at the front of the store. And whats more, most of our lights can be fitted to cycle helmet offering greater versatility. Alternatively, if youre looking for something simple to keep you safe on the road, we have a selection of front and rear bike lights for under £20 which are ideal for everyday use. We are committed to our safety policies and we are unable to offer Fastrack queues at those stores where outside space does not allow for it to be done safely. An excellent choice if you need mountain bike lights. īike collection during your chosen collection day and time. This bicycle light product is available at this price today at Halfords. ![]() This is for the following:Īny prepaid click and collect orders to be picked up on your chosen collection day.Īny of our prepaid services, including our free car and bike checks. Cateye EL135/LD155 Set brings you two shiny, beautiful lights for a safer ride. ![]() Our Click & Collect service means you can order an item online for collection in any of our Stores and choose a day that suits you to collect your order.Īt many of our stores, there will be a Fastrack queuing point available. |
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